Shashank Deep is a professor in Department of Chemistry, Indian Institute of Technology Delhi. Prior to joining IIT Delhi, Prof. Deep has worked as post-doctoral fellow at University of Michigan-Ann Arbor, USA and University of Texas Health Science center at San Antonio, USA. Prof. Deep was elected as a Fellow of both the Royal Society of Chemistry, London, and the Royal Society of Biology, London, in 2020.
Prof. Deep research interest lies at the interface of biology and chemistry. His group has extensively studied aggregation of model proteins as well as neurodegenerative disease linked proteins using various biophysical techniques and MD simulations. These studies have contributed significantly to molecular level understanding of protein aggregation/ fibrillation. His group has also looked in detail the potential of polyphenols as inhibitor for formation of Parkinson linked a- synuclein fibrils formation, Alzheimer related Ab fibril and Cataract related crystallin. Prof. Deep is also involved in devising strategies to make soluble functional protein from inclusion bodies and developing formulation to stabilize them.
Prof. Deep has made significant contribution in exploring and refining methodologies within biophysical, bioanalytical, analytical, and physical chemistry domains. Studies encompass a wide range of techniques, including but not limited to spectroscopy, calorimetry and chromatography. His work has shown the importance of nuanced understanding of the complexities inherent in method development and a deep appreciation for the importance of methodological rigor in scientific inquiry.
Prof. Deep has around 80 publications in reputed journals like Nature structural biology, J Clin Invest, JPC, PCCP, Biochemistry, BBA, ACS Chemical Neurosci., Plos One, Biophysical Journal, JCIS, BBRC etc. Prof. Deep has also co-authored a book “Engineering Chemistry” which has been published by Oxford University Press.
Prof. Deep has also been actively involved in various management, outreach and extension work at national, institute and departmental level. Prof. Deep is on the Board of Studies of various prestigious institutes such as Jamia Milia Islamia and Ashoka University. As chairman of the Hospital Advisory Committee at IIT Delhi during Covid-19 pandemic time, he spearheaded numerous initiatives to combat the challenges posed by the pandemic including organizing vaccination camps, testing facility etc. He has also served as warden of the Jwalamukhi hostel.